Visit Us The world-class physicians and scientists of the UCI Health Chao Family Comprehensive Cancer Center help you fight cancer on all fronts. Our cancer specialists see patients at the following locations: UCI Health Chao Family Comprehensive Cancer Center 101 The City Drive South, Building 23 Orange, CA 92868 Main Phone: 714-456-8000 Fax: 855-211-3729 Maps & Directions › Medical Facilities Map › UCI Health Chao Family Comprehensive Cancer Center and Ambulatory Care building 19208 Jamboree Road Irvine, CA 92612 Phone: 714-456-8000 Maps & Directions › UCI Health Chao Family Comprehensive Cancer Center — Costa Mesa Pacific Medical Plaza 1640 Newport Blvd., Suites 400, 450 and 455 Costa Mesa, CA 92627 Phone: 949-999-2400 Maps & Directions › UCI Health Chao Family Comprehensive Cancer Center — Laguna Hills 3961 Calle de la Magdalena, Suite 200 Laguna Hills, CA 92653 Phone: 949-238-4100 Maps & Directions › UCI Health Chao Family Comprehensive Cancer Center — Yorba Linda 18637 Yorba Linda Blvd. Yorba Linda, CA 92886 Main Phone: 714-790-8600 Maps & Directions › UCI Health — Yorba Linda Infusion Center 18629 Yorba Linda Blvd. Yorba Linda, CA 92886 Main Phone: 714-456-8000 Maps & Directions ›