
Glioblastoma Brain Tumor
A glioblastoma brain tumor is not curable, but it is manageable. We offer pinpointed diagnoses, leading-edge treatments and warmhearted support.
Signs or symptoms of a glioblastoma brain tumor
Glioblastoma symptoms usually include:
- Headaches that feel the most painful in the morning
- Confusion: problems understanding information or difficulty speaking
- Nausea and vomiting
- Personality changes
- Seizures
- Vision problems
- Weakness in arms and legs
When to seek care
If you’re experiencing frequent headaches that feel worse in the morning, please reach out to one of our specialists.
As with any brain tumor, its physical location in your brain influences what symptoms you develop.
Pay special attention if you or your loved ones notice personality changes, you experience unstable moods or have seizures.

Get comprehensive glioblastoma care at UCI Health
A glioblastoma brain tumor can overwhelm your daily life. Let our expert team intercede with quick, decisive action and innovative tools.
Call 714-456-8000 to learn how one of our brain tumor experts can optimize your recovery.
We welcome referrals from community physicians.
To refer a patient to our program, call 714-456-8000 or fill out an online request form. You may also email us at www.ucihealth.org/medical-services/brain-tumor-program/email-us.
One of our brain tumor physicians will return your call within 24 hours. We can see your patient in our offices within 48 hours after insurance approval.

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Glioblastoma treatment at UCI Health
We offer surgery, radiation and chemotherapy, the three most common glioblastoma treatments, plus advanced care options.Why choose UCI Health for glioblastoma care?
Clinician, researcher and co-director of the UCI Health Comprehensive Brain Tumor Program, Dr. Daniela Bota is a nationally and internationally recognized brain tumor expert
Dr. Bota specializes in treating glioblastoma. Results from her research and clinical trial work have changed the way care is delivered at a national level. She is also at the forefront of researching cellular therapy, the next generation of innovative brain tumor treatment.
Dr. Bota’s Brain Tumor Program offers second opinions at a national level.
UCI Health has the only cancer center in Orange County that the National Cancer Institute (NCI) designated as a comprehensive cancer center
The NCI only gives this elite designation to 1.3% of cancer centers. We earned this status by demonstrating consistently excellent care, integrating cancer research into our treatments and serving the local community.
For you, that means state-of-the-art equipment, fellowship-trained teams and highly responsive communication.
We also are one of few hospitals in the nation with a neuro-oncology hospitalist
If you’re here in the hospital, our hospitalist sees you daily. They’ll coordinate your care, provide you with education and monitor your progress. This personalized attention will help you avoid complications and get the most out of your treatments.
In our clinical trials and research work, we have one of the country’s largest immunotherapy programs and conduct other pioneering research
Immunotherapy specifically targets glioblastoma. The size of our program means you’ll benefit from the high volume of our innovative research. By participating in clinical trials, you’re also offering an invaluable service that benefits future patients.