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Find a TrialUCI Health, your source for clinical trials
UCI Health has Orange County’s largest clinical trials program, with 1,000-plus trials and over 3,000 patients enrolled in the past year. By participating in a clinical trial, you help shape the future of medicine. Help us discover and cure!
What are clinical trials?
Clinical trials evaluate the effects of new interventions on health.
Why participate?
Discovery depends on you!
Get involved!
Become a partner in discovering new clinical therapies.
Featured Trials
M6®-C Artificial Cervical Disc Two-Level IDE Pivotal Study
Prospective, concurrently controlled, multi-center study to evaluate the safety and effectiveness of the Spinal Kinetics M6-C™ artificial cervical disc compared to anterior cervical discectomy and fusion (ACDF) for the treatment of contiguous two-level symptomatic cervical radiculopathy at vertebral levels from C3 to C7 with or without spinal cord compression.
A Prospective, Multi-Center Investigation of the DEXA-C Anterior Cervical Interbody System
The DEXA-C Cervical Interbody System is indicated for anterior cervical interbody fusion procedures in skeletally mature patients with degenerative disc disease (DDD) of the cervical spine with accompanying radicular symptoms at one or two contiguous levels from C2-T1.
A Study to Evaluate the Safety and Efficacy of KPI-012 in PCED
This clinical trial evaluates the safety and efficacy of KPI-012 ophthalmic solution in participants with persistent corneal epithelial defect (PCED).
A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T cells (CABA-201) in Subjects with Active Systemic Lupus
To evaluate the safety and efficacy of an investigational cell therapy, CABA-201, that can be given to patients with either LN or SLE without renal involvement, in two separate parallel cohorts, who have active disease.
A Phase II Study of ATR Inhibition in Advanced PD-(L)1-Refractory Merkel Cell Carcinoma
This clinical trial Phase 2 trial tests M1774 alone or with avelumab for patients not responding to anti-PD(L)1 therapy, comparing effectiveness and survival outcomes.
Repurposing Riluzole for Cancer-Related Cognitive Impairment: a Pilot Trial
A phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining the impact of Riluzole therapy on circulating brain derived neuropathic factor (BDNF) levels of breast cancer survivors with cancer related cognitive impairment.
Learn more about clinical trials at UCI Health
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UCI Research News
UCI Health enrolls patient in first U.S. study of medical device for erectile dysfunction
UCI Health has opened the first U.S. clinical trial of a novel radiofrequency device designed to treat erectile dysfunction (ED). Men's health specialist Dr. Faysal A. Yafi is leading the study of Vertica®, a device, designed and manufactured by Ohh-Med Ltd.
2024 Cancer Center Scientific Retreat
This retreat on Friday, November 8, 2024 is open to CFCCC members, clinicians, DOT leaders, shared resource teams, CHOC partners, community equity board members, established community partners, MET trainees, staff, postdoctoral trainees, graduate students and undergraduate students in cancer-related research labs.
Advancing regenerative medicine therapies
University and community guests recently gathered to celebrate the 7,700 square-foot Good Manufacturing Practice facility’s grand opening in Hewitt Hall’s basement on the UC Irvine campus.