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Find a TrialUCI Health, your source for clinical trials
UCI Health has Orange County’s largest clinical trials program, with 1,000-plus trials and over 3,000 patients enrolled in the past year. By participating in a clinical trial, you help shape the future of medicine. Help us discover and cure!
What are clinical trials?
Clinical trials evaluate the effects of new interventions on health.
Why participate?
Discovery depends on you!
Get involved!
Become a partner in discovering new clinical therapies.
Featured Trials
Efficacy and safety study of frexalimab in adults with nonrelapsing secondary progressive MS.
A randomized, double-blind, Phase 3 study comparing efficacy and safety of Frexalimab (SAR441344) to placebo in adult participants with nonrelapsing secondary progressive multiple sclerosis.
Evaluate safety of HyperQureTM, laparoscopic(extravascular) renal denervation therapy in patients with hypertension in the absence of antihypertensive medications (Off-Med).
The HyperQureTM RDN System is developed to overcome the limitations of intravascular RDN using catheters; 1) incomplete renal denervation, 2) risk of endothelial damage due to heat transfer from inside blood vessels by intravascular access, and 3) access limitations due to vascular anatomy and vessel size.
A Study to Evaluate the Safety and Efficacy of KPI-012 in PCED
This clinical trial evaluates the safety and efficacy of KPI-012 ophthalmic solution in participants with persistent corneal epithelial defect (PCED).
A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T cells (CABA-201) in Subjects with Active Systemic Lupus
To evaluate the safety and efficacy of an investigational cell therapy, CABA-201, that can be given to patients with either LN or SLE without renal involvement, in two separate parallel cohorts, who have active disease.
A Phase II Study of ATR Inhibition in Advanced PD-(L)1-Refractory Merkel Cell Carcinoma
This clinical trial Phase 2 trial tests M1774 alone or with avelumab for patients not responding to anti-PD(L)1 therapy, comparing effectiveness and survival outcomes.
Repurposing Riluzole for Cancer-Related Cognitive Impairment: a Pilot Trial
A phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining the impact of Riluzole therapy on circulating brain derived neuropathic factor (BDNF) levels of breast cancer survivors with cancer related cognitive impairment.
Learn more about clinical trials at UCI Health
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UCI Research News
UCI Health enrolls patient in first U.S. study of medical device for erectile dysfunction
UCI Health has opened the first U.S. clinical trial of a novel radiofrequency device designed to treat erectile dysfunction (ED). Men's health specialist Dr. Faysal A. Yafi is leading the study of Vertica®, a device, designed and manufactured by Ohh-Med Ltd.
2024 Cancer Center Scientific Retreat
This retreat on Friday, November 8, 2024 is open to CFCCC members, clinicians, DOT leaders, shared resource teams, CHOC partners, community equity board members, established community partners, MET trainees, staff, postdoctoral trainees, graduate students and undergraduate students in cancer-related research labs.
International Society for Stem Cell Research (ISSCR) Webinar
This webinar will highlight the ISSCR’s "Best Practices for the Translation of PSC-Based Therapies." This resource is being developed for both academics and industry professionals.