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Ph II Olaparib in Patients w/ Metastatic/Advanced Urothelial Carcinoma w/ DNA-Repair Defects

UCI Specialty Area: Cancer
Principal Investigator: Arash Rezazadeh Kalebasty
Official Title: A Phase II Study of Olaparib (AZD2281) in Patients with Metastatic/Advanced Urothelial Carcinoma and Other Genitourinary Tumors with DNA-Repair Defects
A Study On:
Kidney
Urinary Bladder

Study Description

Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with stage II primary invasive cutaneous melanomas (AJCC 8th edition) to determine differences in disease-free survival. A reduction in margins is expected to improve patient quality of life.

Eligibility

Patients must have a stage II primary invasive cutaneous melanoma

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University of California, Irvine - Study Information Sheet

UCI Center for Clinical Research Potential Participant Database

Lead Researcher
Maheswari Senthil, MD
UCI Center for Clinical Research

In the instance of parental permission, “You” refers to “Your child.”

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